Mansonella ozzardi is a parasitic filarial worm that causes mansonelliasis, a neglected tropical disease primarily found in Central and South America and the Caribbean. This parasite is transmitted to humans through the bite of infected blackflies or midges. Once in the bloodstream, M. ozzardi larvae mature into adult worms, which can live for years in the body, releasing microfilariae that circulate in the blood.
Symptoms of mansonelliasis are often mild or asymptomatic, but in some cases, individuals may experience itching, skin rashes, joint pain, headaches, and abdominal discomfort. Chronic infections can lead to persistent skin and subcutaneous symptoms, and while it is generally less severe than other filarial infections, it can impact quality of life, particularly in endemic regions with high transmission rates.
Treatment for mansonelliasis is usually with antiparasitic medications such as ivermectin or diethylcarbamazine (DEC), which help reduce the microfilarial load and alleviate symptoms. Preventive measures focus on vector control, including insecticide use and protective clothing, to minimize exposure to blackflies and midges in endemic areas. Enhanced awareness and diagnosis can help manage and reduce the prevalence of this often-overlooked infection.
