Plasmodium malariae is one of the least common species of the Plasmodium parasite but can still cause a form of malaria characterized by its prolonged course. Unlike the more aggressive P. falciparum, P. malariae infections can persist at low levels in the bloodstream for years without causing significant symptoms, though patients can still experience periodic fevers. The chronic nature of this infection, if untreated, can lead to complications such as nephrotic syndrome (a kidney disorder), particularly in children. Additionally, the long asymptomatic phase allows the parasite to continue being transmitted via mosquitoes.
Eradicating Plasmodium malariae from the body through antimalarial drugs restores normal function and prevents chronic health issues like kidney damage. Effective treatment helps improve immune function and overall vitality. Reducing the prevalence of P. malariae requires sustained mosquito control efforts and early diagnosis, ensuring that communities exposed to malaria risk can maintain better overall health and avoid the long-term consequences of this persistent parasitic infection.
